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what do chief cells secrete

Author

Sophia Vance

Updated on June 14, 2026

The gastric chief cell (also known as a zymogenic cell or peptic cell) is a cell in the stomach that releases pepsinogen and chymosin. Pepsinogen is activated into the digestive enzyme pepsin when it comes in contact with hydrochloric acid produced by gastric parietal cells.

What do chief cells secrete quizlet?

Chief cells secrete Gastric Lipase which functions to break down fats into smaller fatty acids that can be further digested in the intestine.

What do chief cells secrete and what is the function?

Chief cells are the other type of exocrine secretory cell in the stomach. They secrete digestive enzymes that cleave the proteins in food into smaller pieces. Pepsin is secreted as an inactive enzyme called pepsinogen which is secreted by the chief cell.

Do chief cells secrete acid?

Chief cells produce pepsinogen, which is converted to pepsin by hydrochloric acid in the stomach. Parietal cells produce hydrochloric acid, allowing this conversion. Goblet cells produce the mucous lining of the stomach that protects the stomach epithelium from damage from the acidic environment of the gastric lumen.

Do chief cells secrete lipase?

A gastric chief cell (or peptic cell, or gastric zymogenic cell) is a type of gastric gland cell that releases pepsinogen and gastric lipase and is the cell responsible for secretion of chymosin in ruminants.

Do chief cells secrete parathyroid hormone?

Chief cells: The chief cells manage the secretion of parathyroid hormone (PTH). When the cells are viewed, they contain prominent Golgi apparati and a developed endoplasmic reticulum to help with the synthesis and secretion of the hormone.

What are the secretions of the chief cells and parietal cells quizlet?

– The secretions of the mucous, parietal, and chief cells form gastric juice, which totals 2-3 l/d. and mucous neck cells. – The strongly acidic nature of gastric juice kills many microbes, partially denatures proteins in food, and converts pepsinogen into pepsin.

What are chief cells quizlet?

Chief cells secrete pepsinogen, a protease secreted as a zymogen that is activated by the acidic environment of the stomach. G cells secrete gastrin, parietal cells secrete hydrochloric acid and intrinsic factor, and mucous cells secrete alkaline mucus, eliminating the other answer choices.

What do parietal cells secrete?

Parietal cells are responsible for gastric acid secretion, which aids in the digestion of food, absorption of minerals, and control of harmful bacteria.

Why do chief cells secrete pepsinogen?

Specific cells within the gastric lining, known as chief cells, release pepsin in an inactive form, or zymogen form, called pepsinogen. By doing so, the stomach prevents the auto-digestion of protective proteins in the lining of the digestive tract.

What is HCl secreted by?

Hydrochloric acid is the main component of gastric juice and is secreted by the parietal cells of the gastric mucosa in the fundus and corpus.

What secretes gastric lipase?

Immunochemical studies revealed that human gastric lipase (HGL) is secreted by the chief (zymogen) cells of gastric mucosa [4]. HGL takes part in digestion of fats, and it accounts for approximately 40% of preduodenal lipolysis.

Do chief cells secrete intrinsic factor?

Intrinsic factor is a glycoprotein secreted by parietal (humans) or chief (rodents) cells of the gastric mucosa. In humans, it has an important role in the absorption of vitamin B12 (cobalamin) in the intestine, and failure to produce or utilize intrinsic factor results in the condition pernicious anemia.

What do Enterochromaffin like cells secrete?

Abstract. The enterochromaffin-like (ECL) cells of the oxyntic mucosa (fundus) of the stomach produce, store and secrete histamine, chromogranin A-derived peptides such as pancreastatin, and an unanticipated but as yet unidentified peptide hormone.

What do neck cells secrete?

The purpose of mucous neck cells is to secrete mucus.